Hi there,
I simulated many properties of neurons, including their resting membrane potential, action potential kinetics in response to injected current, as well and various other cellular properties. I was inspired to work on this code through fascination in my neuroscience graduate course on neurophysiology, and really I did all this because it’s a mechanism to help me study and learn the intuition behind cellular processes. Sometimes a background in engineering can be helpful in understanding the complex aspects of biology. This code calculates ionic equilibrium potentials with the Nernst equation, looks at membrane response under varying capacitances and resistances, and looks at passive depletion of signal across processes. It also includes original data from Hodgkin & Huxley’s 1952 paper on action potentials to simulate them in neurons under current clamp (some of that code came from University of Michigan). Currents and potentials of individual ions are simulated and able to be modulated in the program to investigate action potentials in a little more fine-grain detail.
All of this is done in Matlab, and I’d be excited if you download the code below and run the program, just don’t judge my programming abilities or lack thereof. (:
Code is located on my GitHub, here.
